Elementary 3D organization of active and silenced E. coli genome Summary This Nature paper uses ultra-high-resolution Micro-C (down to ~10 bp) and complementary methods to map the 3D organisation of…
Multiple oestradiol functions inhibit ferroptosis and acute kidney injury Summary This Nature study shows that female kidneys are intrinsically more resistant to acute kidney injury (AKI) because oestradiol acts by…
Establishment of chromatin architecture interplays with embryo hypertranscription Summary This study maps how three-dimensional (3D) chromatin architecture is established de novo during early mammalian embryogenesis and shows it is tightly…
Clone copy number diversity is linked to survival in lung cancer Summary This Nature paper introduces ALPACA, a computational method that infers allele-specific copy numbers for individual tumour clones from…
NASP modulates histone turnover to drive PARP inhibitor resistance Content summary This Nature paper reports that the histone chaperone NASP stabilises chromatin-released histones and thereby enables resistance to PARP inhibitors…
Expanding the cytokine receptor alphabet reprograms T cells into diverse states Summary This study uses an orthogonal IL-2/IL-2Rβ platform to swap intracellular domains (ICDs) from different cytokine receptors onto a…
The geologic history of marine dissolved organic carbon from iron oxides Summary This paper introduces a new, experimentally calibrated proxy (Fe-OC) for reconstructing past marine dissolved organic carbon (DOC) using…
Acidic oxygen reduction by single-atom Fe catalysts on curved supports Summary This Nature article reports a new Fe/N–C electrocatalyst architecture composed of numerous nanoprotrusions on two-dimensional carbon layers, with single-atom…
Accuracy of rubber-related deforestation maps Summary Hoang et al. reanalyse and critique high-resolution maps of mature rubber plantations produced by Wang et al. (2023). Wang et al. reported a high…
Sun-powered flyers could explore the mysterious mesosphere Summary Researchers describe a one-centimetre solar-powered flyer that levitates using thermal transpiration: two thin, perforated membranes let gas flow from the warm side…
