Establishment of chromatin architecture interplays with embryo hypertranscription Summary This Nature study examines how the de novo assembly of 3D chromatin architecture in early mammalian embryos is tightly coupled to…
Clone copy number diversity is linked to survival in lung cancer Summary This Nature paper introduces ALPACA, a computational method that infers allele- and clone-specific copy-number profiles from multi-sample bulk…
NASP modulates histone turnover to drive PARP inhibitor resistance Summary The study identifies the histone chaperone NASP as a key determinant of cellular response to PARP inhibitors (PARPi). Using haploid…
Expanding the cytokine receptor alphabet reprograms T cells into diverse states Summary This Nature paper describes an engineered, orthogonal IL-2/IL-2Rβ platform that swaps intracellular domains (ICDs) from a wide range…
Acidic oxygen reduction by single-atom Fe catalysts on curved supports Summary The authors report a new Fe/N–C electrocatalyst architecture made of two-dimensional carbon layers decorated with numerous nanoprotrusions that host…
Accuracy of rubber-related deforestation maps Summary Hoang et al. (2025) examine the accuracy of high-resolution rubber plantation maps produced by Wang et al. (2023). They find substantial overestimation of rubber…
Sun-powered flyers could explore the mysterious mesosphere Summary Researchers have demonstrated a one-centimetre-wide, solar‑powered levitating device that needs no moving parts. The tiny flyer uses thermal transpiration — a gas…
Brazilian PhD students opt out of US research opportunities Summary Over the past year a noticeable number of Brazilian PhD students who had planned to carry out research in the…
Controversial quantum-computing paper gets hefty correction — but concerns linger Summary The journal Science has lifted an editorial expression of concern and published a 20-page correction to the supplementary material…
A mind–reading brain implant that comes with password protection Summary A new brain–computer interface (BCI) decodes imagined speech in near real time but only activates when the user thinks a…
