Summary Researchers report one of the first n-type thermoelectric elastomers, produced by combining uniform bulk nanophase separation, thermally activated crosslinking and targeted n-doping in a single material. The resulting material…
Delocalized electrolyte design enables 600 Wh kg−1 lithium metal pouch cells Summary This Nature paper introduces a “delocalised” electrolyte concept that deliberately breaks the dominance of single solvation structures to…
The genomic origin of the unique chaetognath body plan Key points • Chromosome-level genome (257 Mb) and single-cell atlas produced for the arrow worm Paraspadella gotoi, revealing extensive genomic reorganisation…
Elementary 3D organization of active and silenced E. coli genome Summary Using ultra-high-resolution Micro‑C (up to 10 bp) the authors mapped the 3D organisation of the E. coli chromosome and…
Human emissions drive recent trends in North Pacific climate variations Summary This Nature paper finds that the Pacific decadal oscillation (PDO) — the dominant pattern of North Pacific multidecadal climate…
Multiple oestradiol functions inhibit ferroptosis and acute kidney injury Summary This Nature paper reports that female mammals (mice, pigs and human samples) are intrinsically more resistant than males to acute…
Establishment of chromatin architecture interplays with embryo hypertranscription Summary This Nature paper investigates how de novo 3D chromatin architecture and a surge of transcription (hypertranscription) are coordinated during early mammalian…
Clone copy number diversity is linked to survival in lung cancer Summary This Nature paper introduces ALPACA, a computational method that infers allele- and clone-specific copy-number profiles from multi-sample bulk…
NASP modulates histone turnover to drive PARP inhibitor resistance Summary This Nature paper identifies the histone chaperone NASP as a key regulator of resistance to PARP inhibitors (PARPi). Using haploid…
Expanding the cytokine receptor alphabet reprograms T cells into diverse states Key insights • An orthogonal IL-2/IL-2Rβ platform was repurposed to swap intracellular domains (ICDs) from other cytokine receptors onto…
