Rewiring of cortical glucose metabolism fuels human brain cancer growth Summary This study used clinical stable-isotope infusions and metabolic flux analysis (MFA) in human glioma patients and patient-derived mouse models…
Dynamic fibroblast–immune interactions shape recovery after brain injury Summary This Nature paper maps how central nervous system (CNS) fibroblasts respond to brain injury, how they interact with myeloid cells and…
One mother for two species via obligate cross-species cloning in ants Summary This Nature paper reports a striking reproductive system in the harvester ant Messor ibericus. Using field sampling, whole‑genome…
Genetic suppression features ABHD18 as a Barth syndrome therapeutic target Summary This Nature study uses complementary genome-wide genetic screens and biochemical assays to identify ABHD18 as a suppressor of TAFAZZIN…
Multiple overlapping binding sites determine transcription factor occupancy Key Points • The authors developed PADIT-seq, an in vitro transcription/RNA-seq assay that measures transcription factor (TF) affinity to all possible 10-base…
Amygdala–liver signalling orchestrates glycaemic responses to stress Summary This Nature study identifies a previously undescribed neural axis from the medial amygdala (MeA) to the ventromedial hypothalamus (VMH) and onward to…
PICALM Alzheimer’s risk allele causes aberrant lipid droplets in microglia Summary This Nature study uses allele-specific open-chromatin (ASoC) mapping in human iPSC-derived brain cells to pinpoint functional non-coding variants for…
Commensal yeast promotes Salmonella Typhimurium virulence Summary This Nature study shows that the common gut yeast Candida albicans can increase the virulence of Salmonella Typhimurium through a defined molecular interaction.…
Supervised learning in DNA neural networks Summary This Nature paper reports an engineered DNA-based molecular system that performs supervised learning in vitro. The authors design and build a DNA strand-displacement…
3D-printed micro ion trap technology for quantum information applications Summary This paper reports a new fabrication approach for trapped-ion quantum devices using high-resolution 3D printing (two-photon polymerisation) to create micro-scale…
