Cocaine-activated ion channels engineered to break the loop of addiction in rats Summary Researchers have engineered ion channels that are selectively activated by cocaine and that either excite or inhibit…
Ancient DNA connects large-scale migration with the spread of Slavs Summary This Nature study uses newly generated ancient DNA from 591 selected skeletons (555 unique genomes after quality control) across…
Seismic detection of a 600-km solid inner core in Mars Summary This Nature paper presents seismic evidence from the InSight mission that Mars hosts a solid inner core (IC) roughly…
Rewiring of cortical glucose metabolism fuels human brain cancer growth Summary This Nature study used clinical stable-isotope infusions (glucose) in eight patients undergoing glioma resection and multiple patient-derived intracranial mouse…
Dynamic fibroblast–immune interactions shape recovery after brain injury Summary This study maps how central nervous system (CNS) fibroblasts and local immune cells coordinate the brain’s response to injury. Using lineage…
One mother for two species via obligate cross-species cloning in ants Summary This Nature paper reports an unprecedented reproductive system in the harvester ant Messor ibericus. Using population genomics, phylogenetics…
Genetic suppression features ABHD18 as a Barth syndrome therapeutic target Summary This Nature study used genome-wide genetic suppression and CRISPR-based interaction screens in TAZ (tafazzin)-deficient human cells to identify ABHD18,…
Multiple overlapping binding sites determine transcription factor occupancy Summary This Nature paper introduces PADIT-seq (protein affinity to DNA by in vitro transcription and RNA sequencing), a high-throughput assay that measures…
Amygdala–liver signalling orchestrates glycaemic responses to stress Summary This Nature paper identifies a rapid brain→liver pathway that controls blood glucose during acute stress in mice. Neuronal activity in the medial…
PICALM Alzheimer’s risk allele causes aberrant lipid droplets in microglia Summary This Nature paper uses allele-specific open chromatin (ASoC) mapping in human iPSC-derived microglia (iMGs), astrocytes and neurons to nominate…
