Single-cell transcriptomic and genomic changes in the ageing human brain Summary This Nature study combines droplet-based single-nucleus RNA-seq (snRNA-seq), single-cell whole-genome sequencing (scWGS using PTA) and MERFISH spatial transcriptomics on…
Summary The paper from Microsoft Research and collaborators introduces the analog optical computer (AOC), a fully analogue, hybrid opto-electronic platform designed to accelerate both AI inference and combinatorial optimisation on…
Divergent evolutionary strategies pre-empt tissue collision in gastrulation Summary This study combines phylogenetic sampling, live imaging, genetics and optogenetics to show how flies avoid catastrophic tissue collisions during early gastrulation.…
Summary Authors: International Brain Laboratory et al. This paper presents a public, brain-wide electrophysiological dataset and initial analyses from mice performing a standardised, decision-making task. The International Brain Laboratory recorded…
A prudent planetary limit for geologic carbon storage Summary This Nature paper produces a spatially explicit, precautionary estimate of how much CO2 can be stored safely and responsibly in sedimentary…
Summary This Nature paper shows that DNA2 (Dna2 in yeast) is essential not because of a canonical role in Okazaki fragment processing, but because it limits homologous recombination-restarted replication (HoRReR)…
Cas9 senses CRISPR RNA abundance to regulate CRISPR spacer acquisition Summary This Nature paper reports that Cas9 has a previously unrecognised role independent of its guide RNAs: apoCas9 (Cas9 without…
Gitpod reinvents itself as Ona in pivot to AI agent platform Summary Gitpod, the cloud-hosted development environment provider, has rebranded as Ona and repositioned itself as an AI agent platform.…
EU court’s dismissal of US data transfer challenge raises privacy advocates’ ire Summary The European Union General Court (EGC) has dismissed an annulment action brought in 2023 by French lawmaker…
Practical Guide to Cloud Outsourcing Governance: Building an Audit-Ready Plan for Third-Party Risk and Resilience Summary This practical guide helps senior IT leaders build an audit-ready plan for cloud outsourcing…
