One-shot design of functional protein binders with BindCraft Summary BindCraft is an automated pipeline that hallucinates de novo protein binders by backpropagating through AlphaFold2 (AF2) multimer weights, then optimises sequences…
Summary This Nature paper (Hunter et al.) shows that physical confinement from the tumour microenvironment drives melanoma cells to switch from a proliferative, differentiated state to an invasive, undifferentiated state…
Electrically driven lasing from a dual-cavity perovskite device Summary This paper reports the first demonstration of electrically driven lasing from a vertically integrated dual-cavity perovskite device. The design stacks a…
Maternal stress triggers early-life eczema through fetal mast cell programming Summary This Nature study uses mouse models and human cohort data to show that maternal psychological stress during late gestation…
Crystal structures of agonist-bound human cannabinoid receptor CB1 Summary This paper reports high-resolution crystal structures of the human cannabinoid receptor CB1 bound to two agonists (AM11542 and AM841), with coordinates…
Mapping urban gullies in the Democratic Republic of the Congo Summary This Nature paper presents the first nationwide, high-resolution inventory of large urban gullies (UGs) across the Democratic Republic of…
Thioester‑mediated RNA aminoacylation and peptidyl‑RNA synthesis in water Summary This Nature paper reports a chemically plausible, non‑enzymatic route that links simple prebiotic molecules to the two core chemical steps of…
Ultrabroadband on-chip photonics for full-spectrum wireless communications Summary This Nature paper demonstrates a thin-film lithium niobate (TFLN) photonic platform that integrates broadband carrier/local-oscillator (LO) generation, baseband modulation and wireless–photonic conversion…
Retraction Note: Crystal structures of agonist-bound human cannabinoid receptor CB1 Summary The authors have retracted their 2017 Nature article on agonist-bound human cannabinoid receptor CB1 to correct the scientific record…
Daily briefing: Epigenetic atlas shows how ageing tweaks DNA Summary A large new analysis maps how DNA methylation — the addition or removal of methyl groups that can change gene…
