A nanobody specific to prefusion glycoprotein B neutralises HSV-1 and HSV-2 Summary This Nature paper reports the discovery and structural characterisation of a prefusion-specific alpaca-derived nanobody, Nb1_gbHSV, that neutralises both…
A circuit that integrates drive state and social contact to gate mating Summary This study identifies a thalamic gate that times the switch from appetitive to consummatory mating behaviour in…
Spatial joint profiling of DNA methylome and transcriptome in tissues Summary This paper introduces spatial-DMT, a new spatial multi-omics method that simultaneously profiles genome-wide DNA methylation and RNA transcription from…
Patterned invagination prevents mechanical instability during gastrulation Content summary This study shows that the cephalic furrow — a prominent but apparently transient epithelial fold at the head–trunk boundary in Drosophila…
Divergent evolutionary strategies pre-empt tissue collision in gastrulation Summary This study (Dey et al., Nature 2025) combines phylogenetic sampling, live imaging and genetic and optogenetic perturbations across flies to show…
Analog optical computer for AI inference and combinatorial optimization Key Points • The paper introduces the Analog Optical Computer (AOC): an all-analog opto-electronic platform that runs iterative fixed-point searches to…
Single-cell transcriptomic and genomic changes in the ageing human brain Summary This study combines droplet-based single-nucleus RNA sequencing (snRNA-seq), single-cell whole-genome sequencing (scWGS using PTA) and MERFISH spatial transcriptomics on…
A prudent planetary limit for geologic carbon storage Summary This Nature paper produces a spatially explicit, precautionary estimate of how much CO2 we should prudently store in sedimentary basins worldwide.…
A brain-wide map of neural activity during complex behaviour Summary This paper from the International Brain Laboratory presents a publicly available, brain-wide electrophysiological dataset recorded while mice performed a standardised…
Inside a mosquito factory Summary This Nature Video story visits a large rearing facility in Curitiba, Brazil, that breeds millions of Aedes aegypti mosquitoes each week to fight mosquito-borne diseases.…
