Genetic suppression features ABHD18 as a Barth syndrome therapeutic target Summary This Nature paper reports a genome-wide genetic suppression search that identifies ABHD18 as a modulator of the Barth syndrome…
Analog optical computer for AI inference and combinatorial optimisation Summary The paper presents the analog optical computer (AOC), an opto-electronic, fully analogue platform that performs iterative fixed-point searches to accelerate…
Single-cell transcriptomic and genomic changes in the ageing human brain Summary This study uses single-nucleus RNA-seq (snRNA-seq), single-cell whole-genome sequencing (scWGS) and MERFISH spatial transcriptomics to map transcriptomic and somatic‑mutation…
A circuit that integrates drive state and social contact to gate mating Summary This paper identifies a thalamic gating circuit that times the switch from appetitive to consummatory male mating…
A brain-wide map of neural activity during complex behaviour Summary This paper from the International Brain Laboratory presents an open, single-laboratory-standardised dataset of brain-wide electrophysiology in mice performing a perceptual…
Divergent evolutionary strategies pre-empt tissue collision in gastrulation Summary This study combines comparative embryology, genetics, optogenetics and quantitative imaging to show how fly species avoid destructive tissue collisions during early…
Inside a mosquito factory Summary In Curitiba, Brazil, a large production facility is rearing millions of Aedes mosquitoes designed to reduce disease transmission. The insects released from this site are…
DNA2 enables growth by restricting recombination-restarted replication Summary This Nature paper shows that DNA2 — a conserved nuclease/helicase — is essential for eukaryotic cell proliferation because it suppresses recombination-restarted replication…
Summary This Nature paper provides a spatially explicit, precautionary estimate of how much CO2 can prudently be stored in sedimentary basins worldwide. Starting from a technical potential of ~11,800 GtCO2,…
FTC fines toy manufacturer for allowing Chinese third-party to collect kids’ data Summary The US Justice Department filed a complaint against Chinese toy maker Apitor after a referral from the…
