GTP release-selective agonists prolong opioid analgesic efficacy Summary This Nature study shows that G-protein-coupled receptors (GPCRs) can drive not only GDP→GTP exchange on Gα proteins but also catalyse the release…
Programmable 200 GOPS Hopfield-inspired photonic Ising machine Article Date: 17 December 2025 URL: https://www.nature.com/articles/s41586-025-09838-7 Summary This Nature paper presents a room-temperature optoelectronic-oscillator (OEO) photonic Ising machine inspired by Hopfield networks.…
An integrated view of the structure and function of the human 4D nucleome Summary Article Date: 17 December 2025 Article URL: https://www.nature.com/articles/s41586-025-09890-3 Article Title: An integrated view of the structure…
Palaeometabolomes yield biological and ecological profiles at early human sites Article Meta Article Date: 2025-12-18 Article URL: https://www.nature.com/articles/s41586-025-09843-w Article Image: (not provided) Summary This Nature paper introduces and applies the…
Astrocyte CCN1 stabilizes neural circuits in the adult brain Article meta Article Date: 17 December 2025 Article URL: https://www.nature.com/articles/s41586-025-09770-w Article Image: https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41586-025-09770-w/MediaObjects/41586_2025_9770_Fig1_HTML.png Summary This study identifies CCN1 (also called CYR61),…
The global hydrogen budget Summary This Nature paper provides the first comprehensive, bottom-up global budget for atmospheric molecular hydrogen (H2) covering trends from 1990–2020 and a detailed gridded budget for…
Mazdutide versus placebo in Chinese adults with type 2 diabetes Article Date: 17 December 2025 Article URL: https://www.nature.com/articles/s41586-025-10026-w Article Image: Header image Summary This Phase 3 randomised trial (DREAMS-1) assessed…
Transient hepatic reconstitution of trophic factors enhances aged immunity Article Date: 17 December 2025 Article URL: https://www.nature.com/articles/s41586-025-09873-4 Article Image: Summary This Nature paper reports a clever, disease-agnostic strategy to counter…
Gene-specific selective sweeps are pervasive across human gut microbiomes Summary This Nature paper introduces a new LD-based statistic, iLDS (integrated LD score), to detect gene-specific selective sweeps driven by recombination…
New spyware discovered on Belarusian journalist’s phone after interrogation Summary Forensic investigators at Reporters Without Borders (RSF) found a previously unknown Android-targeting spyware on a Belarusian journalist’s phone. The malware,…
