Tumour-reactive heterotypic CD8 T cell clusters from clinical samples Summary This Nature paper reports that heterotypic clusters — physical conjugates of CD8+ T cells with tumour cells and/or antigen-presenting cells…
Integrator dynamics in the cortico-basal ganglia loop for flexible motor timing Article meta Article Date: 19 November 2025 Source URL: https://www.nature.com/articles/s41586-025-09778-2 Image: Summary This Nature paper dissects how the frontal…
Hepatic zonation determines tumorigenic potential of mutant β-catenin Summary Published: 19 November 2025 — Raven et al. use sophisticated mouse mosaics, spatial transcriptomics and ribosome profiling to show that the…
Electro-generated excitons for tunable lanthanide electroluminescence Summary This Nature paper reports a ligand-engineered nanohybrid strategy that activates efficient electroluminescence (EL) from insulating lanthanide fluoride nanocrystals (NaGdF4:X) by decoupling charge transport…
Rewiring an olfactory circuit by altering cell-surface combinatorial code Article Date: 19 November 2025 Article URL: https://www.nature.com/articles/s41586-025-09769-3 Article Image: Figure 1 Summary This study demonstrates that altering a small combinatorial…
The Asymmetric Synthesis of an Acyclic N-Stereogenic Amine Summary Published: 19 November 2025 Authors: Chendan Zhu, Sayantani Das, Marie Sophie Sterling, Nobuya Tsuji, Spencer J. Léger, Frank Neese, Chandra Kanta…
Connectivity underlying motor cortex activity during goal-directed behaviour Summary This Nature paper maps how microcircuit connectivity in mouse motor cortex shapes neural activity during a goal-directed, multidirectional tongue-reaching task. The…
Prime editing-installed suppressor tRNAs for disease-agnostic genome editing Article Date: 19 November 2025 Article URL: https://www.nature.com/articles/s41586-025-09732-2 Article Image: Summary This study describes PERT (prime editing-mediated readthrough of premature termination codons),…
ZAK activation at the collided ribosome Summary This Nature paper uses cryo-electron microscopy, CLIP-seq and biochemical/mutational analysis to show how the MAP3K ZAK (ZAKα) recognises and is activated by collided…
Repulsions instruct synaptic partner matching in an olfactory circuit Article Date: 19 November 2025 Article URL: https://www.nature.com/articles/s41586-025-09768-4 Main image: Summary This study uses transcriptome-guided genetics in Drosophila to show that…
