Multiple overlapping binding sites determine transcription factor occupancy Summary The authors introduce PADIT-seq (protein affinity to DNA by in vitro transcription and RNA sequencing), a high-throughput in vitro assay that…
Genetic suppression features ABHD18 as a Barth syndrome therapeutic target Summary This Nature paper reports a genome-wide genetic suppression search that identifies ABHD18 as a modulator of the Barth syndrome…
Inside a mosquito factory Summary In Curitiba, Brazil, a large production facility is rearing millions of Aedes mosquitoes designed to reduce disease transmission. The insects released from this site are…
Cas9 senses CRISPR RNA abundance to regulate CRISPR spacer acquisition Summary This Nature paper reports a previously unknown, RNA-independent role for Cas9 in controlling CRISPR spacer acquisition. Using Neisseria as…
‘Huge architectural change’ to JetBrains ReSharper cuts Visual Studio freezes Summary JetBrains has introduced an out-of-process (OOP) engine for ReSharper in the 2025.2 preview that substantially improves Visual Studio responsiveness.…
The New Dolby Vision 2 HDR Standard is Probably Going To Be Controversial Summary Dolby has announced Dolby Vision 2, a major update to its HDR platform that adds two…
The New Dolby Vision 2 HDR Standard is Probably Going To Be Controversial Summary Dolby Vision 2 introduces two headline features intended to address common TV viewing complaints: Content Intelligence,…
Summary Microsoft has published the assembly-language source for its 1976 6502 BASIC (version 1.1) on GitHub under the MIT Licence. The release comprises 6,955 lines of 6502 assembly, includes conditional…
The New Dolby Vision 2 HDR Standard is Probably Going To Be Controversial Summary Dolby Vision 2 introduces two headline features that are likely to split opinion. Content Intelligence uses…
The New Dolby Vision 2 HDR Standard is Probably Going To Be Controversial Summary Dolby has announced Dolby Vision 2, an update to its HDR ecosystem that adds AI-driven image…
