Genetic suppression features ABHD18 as a Barth syndrome therapeutic target Summary This Nature paper reports genome-wide genetic screens that identify ABHD18 as a genetic suppressor and potential therapeutic target for…
Multiple overlapping binding sites determine transcription factor occupancy Summary This Nature paper introduces PADIT-seq, a high-throughput in vitro assay that measures transcription factor (TF) affinity to every possible 10-base DNA…
Divergent evolutionary strategies pre-empt tissue collision in gastrulation Summary This Nature paper (Dey et al., 2025) shows that a transient epithelial fold called the cephalic furrow (CF) is a cyclorrhaphan…
Inside a mosquito factory Summary There’s a large facility in Curitiba, Brazil, mass-rearing millions of mosquitoes — roughly producing one kilo of mosquito eggs per week — to fight mosquito-borne…
Cas9 senses CRISPR RNA abundance to regulate CRISPR spacer acquisition Summary This Nature paper reports that Cas9 — best known as an RNA-guided nuclease — has an additional, RNA-independent role:…
Daily briefing: Epigenetic atlas shows how ageing tweaks DNA Summary By Flora Graham — Nature Briefing (02 September 2025) A large analysis mapping DNA methylation across the adult lifespan provides…
A mammoth toothache: bacterial community discovered in mouth of ancient mammal Summary Genetic sequencing of teeth, bones and skin from 483 woolly and steppe mammoths has revealed the oldest host-associated…
Is this the future of food? ‘Sexless’ seeds that could transform farming Summary Researchers are close to engineering apomixis — the production of clonal, ‘sexless’ seeds — in major crops.…
A way to determine how partial charges of atoms in a molecule are distributed Summary Researchers have developed an experimental approach to map the subtle partial charges on atoms within…
Liquid-crystal specs refocus with the push of a button Summary Researchers have devised a way to electronically switch the focal strength of spectacles using liquid-crystal technology, allowing wearers who mix…
