Amygdala–liver signalling orchestrates glycaemic responses to stress Summary This Nature paper identifies a previously unrecognised neural axis from the medial amygdala (MeA) to the ventromedial hypothalamus (VMH) that drives rapid…
Multiple overlapping binding sites determine transcription factor occupancy Summary This Nature paper introduces PADIT-seq, an in vitro transcription–sequencing assay that measures transcription factor (TF) binding to all possible 10-base sequences.…
3D-printed micro ion trap technology for quantum information applications Summary This Nature paper reports the development and characterisation of micro ion traps manufactured by high-resolution 3D printing (two-photon polymerisation) and…
Commensal yeast promotes Salmonella Typhimurium virulence Summary This Nature study shows that the common gut yeast Candida albicans can increase the virulence of Salmonella Typhimurium. In mouse models and in…
Adaptive and context-aware volumetric printing Summary This paper introduces GRACE (Generative, Adaptive, Context-Aware 3D Printing), a workflow that combines tomographic volumetric printing with light-sheet imaging, computer vision and parametric modelling…
Spatial joint profiling of DNA methylome and transcriptome in tissues Summary This paper presents spatial-DMT, a spatial multi-omics method that simultaneously profiles the DNA methylome and the transcriptome from the…
A nanobody specific to prefusion glycoprotein B neutralizes HSV-1 and HSV-2 Summary This paper reports the discovery and structural characterisation of a prefusion-specific nanobody (Nb1_gbHSV) that neutralises herpes simplex virus…
Single-cell transcriptomic and genomic changes in the ageing human brain Summary This study merges droplet-based single-nucleus RNA-seq (snRNA-seq; 367,317 nuclei), single-cell whole-genome sequencing (scWGS) and MERFISH spatial transcriptomics from fresh-frozen…
Cas9 senses CRISPR RNA abundance to regulate CRISPR spacer acquisition Summary This Nature article reports a non-canonical role for Cas9: as an apo-protein sensor of crRNA abundance that regulates spacer…
New Study Proves EVs Are Always Cleaner Than Gas Cars Summary The University of Michigan has published a lifecycle study and an interactive calculator that compares greenhouse‑gas emissions for different…
