A way to determine how partial charges of atoms in a molecule are distributed Summary Researchers have demonstrated an experimental route to measure atomic partial charges in molecules by exploiting…
Depriving brain tumours of an amino acid could enhance chemotherapy Summary Glioblastoma, the most aggressive adult brain tumour, diverts glucose-derived carbon into pathways that fuel invasion and growth and also…
Compression causes cancer cells to start spreading Summary Researchers using a zebrafish model of melanoma show that mechanical compression from surrounding tissues can flip cancer cells from a proliferative state…
The diversity of microbial enzymes that turn a pollutant into an inert gas Summary Reductase enzymes catalyse the conversion of the greenhouse gas nitrous oxide (N2O) into harmless dinitrogen (N2).…
Cocaine-activated ion channels engineered to break the loop of addiction in rats Summary Researchers have engineered ion channels that are selectively activated by cocaine and that either excite or inhibit…
Damaged bridges flex and twist to prevent collapse Summary Steel truss bridges — made from interconnected members — can sometimes survive the sudden loss of a load-bearing element by activating…
Genetic suppression features ABHD18 as a Barth syndrome therapeutic target Summary This Nature study used genome-wide genetic suppression and CRISPR-based interaction screens in TAZ (tafazzin)-deficient human cells to identify ABHD18,…
Multiple overlapping binding sites determine transcription factor occupancy Summary This Nature paper introduces PADIT-seq (protein affinity to DNA by in vitro transcription and RNA sequencing), a high-throughput assay that measures…
Adaptive and context-aware volumetric printing Summary This Nature paper introduces GRACE (Generative, Adaptive, Context-Aware 3D Printing), a workflow that combines tomographic volumetric printing with light-sheet imaging, computer vision and parametric…
3D-printed micro ion trap technology for quantum information applications Summary This Nature paper demonstrates a fabrication route for micro ion traps using high-resolution 3D printing (two-photon polymerisation) combined with metal…
