NSD2 inhibitors rewire chromatin to treat lung and pancreatic cancers Summary This Nature paper reports discovery and preclinical characterisation of selective small-molecule inhibitors of the histone methyltransferase NSD2 (notably IACS-17596…
High-accuracy laser spectroscopy of H2+ and the proton–electron mass ratio Summary This paper reports Doppler-free, high-accuracy laser spectroscopy of a rovibrational vibrational overtone of the homonuclear molecular ion H2+. Using…
Novel assembly of a head–trunk interface in the sister group of jawed vertebrates Summary This Nature paper (Miyashita et al., 2025) presents high-resolution, non‑destructive synchrotron X‑ray microtomography of the Devonian…
RNA N-glycosylation enables immune evasion and homeostatic efferocytosis Summary This Nature paper reports that small RNAs bearing N-linked glycans (“glycoRNAs”) reside on cell surfaces and in circulation, and that those…
In situ light-field imaging of octopus locomotion reveals simplified control Summary Researchers deployed a remotely operated vehicle (ROV) equipped with a light-field imaging system called EyeRIS plus an ultra-high-definition science…
Whole-genome sequencing of 490,640 UK Biobank participants Summary The UK Biobank has completed deep whole-genome sequencing (WGS) for 490,640 participants (mean coverage 32.5×), producing a resource that identifies ~1.5 billion…
Therapeutic genetic restoration through allogeneic brain microglia replacement Summary This study reports a brain-restricted allogeneic microglia-replacement approach that avoids toxic myeloablative conditioning typically required for haematopoietic stem cell transplantation (HCT).…
Reply to: Inconclusive proof of ferroelectricity in peptide-VDF ribbons Summary Yang et al. respond to a Comment by Kemerink and colleagues that questioned the evidence for ferroelectricity in peptide‑programmed vinylidene…
What is a smart home? Everything you need to know Summary A smart home is a residence that uses internet‑connected devices to enable remote monitoring and control of appliances and…
Google Will Now Let You Pick Your Top Sources For Search Results Summary Google has introduced a new “Preferred Sources” feature in the US and India that lets users pick…
