Synthetic α-synuclein fibrils replicate in mice causing MSA-like pathology Article Date: 05 November 2025 Article URL: https://www.nature.com/articles/s41586-025-09698-1 Article Image: Figure 1 (source) Summary This Nature paper reports a synthetic α-synuclein…
Lineage-resolved atlas of the developing human cortex Article Date: 05 November 2025 Article URL: https://www.nature.com/articles/s41586-025-09033-8 Article Image: Summary This study builds a lineage-resolved single-cell atlas of the human developing neocortex…
Continuous cell-type diversification in mouse visual cortex development Article metadata Article Date: 05 November 2025 Article URL: https://www.nature.com/articles/s41586-025-09644-1 Article Image: Summary This Nature paper from the Allen Institute presents a…
The new frontier in understanding human and mammalian brain development Article metadata Article Date: 2025 Article URL: https://www.nature.com/articles/s41586-025-09652-1 Article Title: The new frontier in understanding human and mammalian brain development…
Lymph node environment drives FSP1 targetability in metastasizing melanoma Summary This Nature study reveals that the lymph node (LN) microenvironment reconfigures ferroptosis-defence systems in metastasising melanoma, shifting cells away from…
Atomically accurate de novo design of antibodies with RFdiffusion Summary This Nature paper reports a specialised, fine‑tuned version of RFdiffusion that can design epitope‑specific antibody domains (VHHs and scFvs) de…
Myriad Aryne Derivatives from Carboxylic Acids Summary Researchers report a practical aryne precursor made in a single step from common carboxylic acids. The precursor is activated by blue light or…
Targeting FSP1 triggers ferroptosis in lung cancer Summary This Nature study demonstrates that disabling the ferroptosis suppressor FSP1 (AIFM2) is sufficient to trigger lipid-peroxide-driven cell death and dramatically restrict lung…
Secretome translation shaped by lysosomes and lunapark-marked ER junctions Article Meta Article Date: 05 November 2025 Article URL: https://www.nature.com/articles/s41586-025-09718-0 Article Title: Secretome translation shaped by lysosomes and lunapark-marked ER junctions…
Assessing phylogenetic confidence at pandemic scales Summary This paper introduces SPRTA (subtree pruning and regrafting-based tree assessment), a new branch-support measure designed for pandemic-scale phylogenetics. Unlike traditional topological support measures…
