Rewiring of cortical glucose metabolism fuels human brain cancer growth Summary This Nature paper uses clinical stable-isotope infusions in patients and complementary tracer studies in mouse orthotopic models to map…
Dynamic fibroblast–immune interactions shape recovery after brain injury Summary This study maps how central nervous system (CNS) fibroblasts respond to brain injury, how they communicate with immune cells, and how…
One mother for two species via obligate cross-species cloning in ants Summary This Nature paper reports an unprecedented reproductive system in the harvester ant Messor ibericus. Using population genomics (c.390…
Genetic suppression features ABHD18 as a Barth syndrome therapeutic target Key points • Genome-wide genetic suppression screens identify ABHD18 as a modifier that mitigates defects caused by loss of TAZ…
Multiple overlapping binding sites determine transcription factor occupancy Key points • The authors developed PADIT-seq, an in vitro transcription–sequencing assay that measures transcription factor (TF) affinity to all possible 10-base…
Amygdala–liver signalling orchestrates glycaemic responses to stress Summary This Nature study identifies a previously unrecognised amygdala–hypothalamus–liver axis that rapidly drives stress-induced hyperglycaemia in mice. Neuronal activity in the medial amygdala…
PICALM Alzheimer’s risk allele causes aberrant lipid droplets in microglia Summary This study uses allele-specific open chromatin (ASoC) mapping in human iPSC-derived microglia (iMGs), astrocytes and neurons to functionally interpret…
Commensal yeast promotes Salmonella Typhimurium virulence Summary This Nature paper describes a mechanistic, interkingdom interaction in the gut between the common fungus Candida albicans, the enteric bacterial pathogen Salmonella Typhimurium…
Supervised learning in DNA neural networks Summary This Nature paper (Cherry & Qian, 2025) reports an engineered DNA-based molecular system that can perform supervised learning and then classify new molecular…
3D-printed micro ion trap technology for quantum information applications Summary This Nature paper describes a fabrication and characterisation workflow for 3D-printed micro ion traps intended for trapped-ion quantum information systems.…
