Cocaine-activated ion channels engineered to break the loop of addiction in rats Summary Ion channels have been engineered to be selectively activated by cocaine. These designer channels can either stimulate…
‘Almost unimaginable’: these ants are different species but share a mother Summary Researchers report that queens of the Iberian harvester ant (Messor ibericus) can produce male offspring belonging to a…
Rewiring of cortical glucose metabolism fuels human brain cancer growth Summary This Nature paper uses clinical stable-isotope infusions in patients and complementary tracer experiments in mouse models to compare how…
Dynamic fibroblast–immune interactions shape recovery after brain injury Summary This Nature paper maps how central nervous system (CNS) fibroblasts respond to brain injury, the immune partners that shape their states,…
One mother for two species via obligate cross-species cloning in ants Summary Researchers report a previously unknown reproductive system in the harvester ant Messor ibericus. Queens of M. ibericus produce…
Genetic suppression features ABHD18 as a Barth syndrome therapeutic target Summary This Nature paper reports a multi-platform genetic and biochemical study that identifies ABHD18 — an α/β-hydrolase domain protein —…
Multiple overlapping binding sites determine transcription factor occupancy Summary This Nature paper introduces PADIT-seq, a high-throughput in vitro assay that measures transcription factor (TF) affinity to all possible 10-base-pair DNA…
Amygdala–liver signalling orchestrates glycaemic responses to stress Summary This Nature paper identifies a previously unrecognised neural axis from the medial amygdala (MeA) to the ventromedial hypothalamus (VMH) that rapidly drives…
Spatial joint profiling of DNA methylome and transcriptome in tissues Summary This paper presents spatial‑DMT, a new spatial multi‑omics method that simultaneously profiles the DNA methylome (mCG and mCH) and…
Summary This paper identifies a thalamic gate that integrates internal sexual drive and tactile contact to time the switch from appetitive to consummatory mating behaviours in male mice. The authors…
