Single-cell transcriptomic and genomic changes in the ageing human brain Summary This study combines droplet-based single-nucleus RNA-sequencing (snRNA-seq), single-cell whole-genome sequencing (scWGS, using PTA) and MERFISH spatial transcriptomics on human…
Analog optical computer for AI inference and combinatorial optimization Summary The paper introduces the Analog Optical Computer (AOC), an all-analog hybrid opto-electronic platform that runs iterative fixed-point searches to accelerate…
Divergent evolutionary strategies pre-empt tissue collision in gastrulation Summary This Nature paper (Dey et al., 2025) combines phylogenetically informed sampling, live imaging, genetics and optogenetics to explain how different flies…
A brain-wide map of neural activity during complex behaviour Summary This Nature paper from the International Brain Laboratory (IBL) presents a publicly available, standardised, brain‑wide electrophysiological dataset recorded while mice…
A prudent planetary limit for geologic carbon storage Summary This Nature paper produces a spatially explicit, precautionary estimate of how much CO2 can reasonably be stored in sedimentary basins worldwide…
DNA2 enables growth by restricting recombination-restarted replication Summary This Nature paper shows that the conserved nuclease–helicase DNA2 is essential for cell proliferation because it prevents excessive recombination-restarted replication (HoRReR) at…
‘How is this possible?’ — two species birthed by one mother Summary This Nature News item reports on a new study showing that Iberian harvester ant queens (Messor ibericus) can…
Cas9 senses CRISPR RNA abundance to regulate CRISPR spacer acquisition Summary This Nature study shows that Cas9 performs a previously unknown, RNA-independent role: sensing the abundance of CRISPR RNAs (crRNA…
Azure Arc setup tips for on-premises server management Summary This tutorial explains how to use Azure Arc to manage on-premises Windows Server machines and to run patch management via Azure…
Google Hit With $3.45 Billion EU Antitrust Fine Over Adtech Practices Summary The European Commission has fined Alphabet’s Google $3.45 billion for anti-competitive behaviour in its online adtech business, finding…
