PICALM Alzheimer’s risk allele causes aberrant lipid droplets in microglia Summary This study uses allele-specific open chromatin (ASoC) mapping in human iPSC-derived microglia (iMGs), astrocytes and neurons to functionally interpret…
Amygdala–liver signalling orchestrates glycaemic responses to stress Summary This Nature study identifies a previously unrecognised amygdala–hypothalamus–liver axis that rapidly drives stress-induced hyperglycaemia in mice. Neuronal activity in the medial amygdala…
3D-printed micro ion trap technology for quantum information applications Summary This Nature paper describes a fabrication and characterisation workflow for 3D-printed micro ion traps intended for trapped-ion quantum information systems.…
Supervised learning in DNA neural networks Summary This Nature paper (Cherry & Qian, 2025) reports an engineered DNA-based molecular system that can perform supervised learning and then classify new molecular…
Commensal yeast promotes Salmonella Typhimurium virulence Summary This Nature paper describes a mechanistic, interkingdom interaction in the gut between the common fungus Candida albicans, the enteric bacterial pathogen Salmonella Typhimurium…
Training of physical neural networks Summary This Nature review surveys the emerging field of physical neural networks (PNNs) — analogue hardware systems that perform neural-like computation using physical dynamics (optical,…
Summary This Nature paper introduces GRACE (Generative, Adaptive, Context-Aware 3D Printing), a workflow that fuses tomographic volumetric printing with light-sheet imaging, computer vision and parametric modelling so printers can scan…
Patterned invagination prevents mechanical instability during gastrulation Summary This paper investigates the developmental role and evolutionary origin of the cephalic furrow — a patterned epithelial invagination at the head–trunk boundary…
Brain-wide representations of prior information in mouse decision-making Summary This Nature paper from the International Brain Laboratory examines where and how prior information (the animal’s expectations about which side a…
A nanobody specific to prefusion glycoprotein B neutralizes HSV-1 and HSV-2 Summary This paper reports the discovery and structural characterisation of a prefusion‑specific nanobody (Nb1_gbHSV) that potently neutralises herpes simplex…
